{"id":15037,"date":"2026-10-02T15:05:00","date_gmt":"2026-10-02T14:05:00","guid":{"rendered":"https:\/\/thehotedit.com\/index.php\/2026\/10\/02\/scientists-find-surprise-link-between-grey-hair-and-cancer\/"},"modified":"2026-10-02T15:05:00","modified_gmt":"2026-10-02T14:05:00","slug":"scientists-find-surprise-link-between-grey-hair-and-cancer","status":"publish","type":"post","link":"https:\/\/thehotedit.com\/index.php\/2026\/10\/02\/scientists-find-surprise-link-between-grey-hair-and-cancer\/","title":{"rendered":"Scientists find surprise link between grey hair and cancer"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div id=\"main\">\n<div id=\"mos-2af265f1-2994-41f3-87a9-f397107cadf2\" style=\"display: contents;\">\n<div class=\"bookmark-experience\" id=\"bookmark-modal-b20f74c5fb93M1rt9l4hjvZ4b3\">\n<div class=\"modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"bookmark-headline\">\n    <button class=\"close-btn\" type=\"button\" aria-label=\"Close\" onclick=\"this.closest('.bookmark-experience').style.display='none'\"><br \/>\n      <span class=\"close-btn__icon\" aria-hidden=\"true\"\/><br \/>\n    <\/button><\/p>\n<div class=\"logo-row\">\n      \n    <\/div>\n<p class=\"body-text\">Want to bookmark your favourite articles and stories to read or reference later? Start your Independent Membership today.<\/p>\n<p>        <a target=\"_blank\" href=\"\/subscribe?regSourceMethod=Bookmarks\" class=\"subscribe-link\" target=\"_parent\">Join today<\/a><\/p>\n<p class=\"login-copy\">\n      Already a member?<br \/>\n      <a target=\"_blank\" href=\"#\" class=\"login-link login-trigger\" external-event=\"openLogin\">Log in<\/a>\n    <\/p>\n<\/p><\/div>\n<\/div>\n<\/div>\n<div class=\"hydrate-root sc-1ihz57b-0\" data-component=\"Newsletter\" data-loading=\"lazy\" data-theme-name=\"independent\">\n<div data-theme-wrapper=\"independent\" style=\"display:contents\">\n<aside class=\"sc-y4bm30-0 jwWhkK newsletter-component sc-1ge0fwe-1\" data-newsletter-key=\"receiveWellness\">\n<div class=\"sc-y4bm30-2 kcLSBk\"><img decoding=\"async\" src=\"https:\/\/static.independent.co.uk\/static-assets\/images\/newsletters\/wellEnough1_1.png\" loading=\"lazy\" alt=\"Well Enough\" class=\"sc-1mc30lb-0 ggpMaE\"\/><\/div>\n<div class=\"sc-y4bm30-1 inRDZn\">\n<div class=\"sc-y4bm30-3\">\n<div class=\"sc-y4bm30-4 hfveGa\">\n<p><h3 class=\"sc-y4bm30-5 sc-y4bm30-6 fvoxRM cLEJmn\">Get the Well Enough newsletter with Harry Bullmore for tips on living a healthier, happier and longer life<\/h3>\n<h3 class=\"sc-y4bm30-5 sc-y4bm30-8 fvoxRM iTZFOX\">Get the Well Enough email with Harry Bullmore<\/h3>\n<h3 class=\"sc-y4bm30-5 sc-y4bm30-7 fvoxRM iGYpOF\">Get the Well Enough email with Harry Bullmore<\/h3>\n<\/p>\n<p><svg class=\"sc-eaj12q-0 loKJGs sc-culv3z-0 eifaJK sc-1ix0cah-0 PYnPb sc-y4bm30-10 fUEDPX\" viewbox=\"0 0 32 32\"><use href=\"#600f53465147d717\"\/><\/svg><\/div>\n<div class=\"sc-y4bm30-2 kcLSBk sc-y4bm30-9 iQYNfz\"><img decoding=\"async\" src=\"https:\/\/static.independent.co.uk\/static-assets\/images\/newsletters\/wellEnough1_1.png\" loading=\"lazy\" alt=\"Well Enough\" class=\"sc-1mc30lb-0 ggpMaE\"\/><\/div>\n<\/div>\n<\/div>\n<\/aside>\n<\/div>\n<\/div>\n<p>Grey hair is an inevitable hallmark of ageing. It\u2019s a visual reminder of the passing years and all the bodily changes that accompany it.<\/p>\n<p>But emerging scientific research is challenging this simple narrative \u2013 revealing that those <a target=\"_blank\" href=\"https:\/\/www.independent.co.uk\/extras\/indybest\/fashion-beauty\/hair\/best-shampoos-for-grey-hair-b1890704.html\">silver strands on our heads <\/a>could be an outward sign of our body\u2019s own intricate defences against <a target=\"_blank\" href=\"https:\/\/www.independent.co.uk\/topic\/cancer\">cancer<\/a>.<\/p>\n<p>A new study in mice has uncovered the remarkable ways in which our bodies manage cellular damage \u2013 <a target=\"_blank\" href=\"https:\/\/www.independent.co.uk\/life-style\/health-and-families\/cancer-cause-ageing-alcohol-smoking-risk-b2831955.html\">a process key in both ageing and cancer.<\/a> In ageing, cellular damage gradually weakens and disrupts cell function. In cancer, unrepaired or faulty cells can trigger abnormal growth and tumour formation.<\/p>\n<p>The work here has highlighted a surprising connection between the loss of pigment in our hair and the mechanisms that can keep deadly cancers at bay.<\/p>\n<div class=\"sc-awdjp1-2 cbpRGD sc-awdjp1-3 image align-center\">\n<figure class=\"sc-1cbdeug-0 cXcwgU\">\n<div data-gallery-length=\"3\" class=\"sc-awdjp1-0 citgSe\"><img decoding=\"async\" src=\"https:\/\/static.independent.co.uk\/2025\/09\/05\/10\/04090729-7fd0094d-2ce1-4b12-94f6-1294198ccfb0.jpg\" srcset=\"https:\/\/static.independent.co.uk\/2025\/09\/05\/10\/04090729-7fd0094d-2ce1-4b12-94f6-1294198ccfb0.jpg?quality=75&amp;width=320&amp;auto=webp 320w, https:\/\/static.independent.co.uk\/2025\/09\/05\/10\/04090729-7fd0094d-2ce1-4b12-94f6-1294198ccfb0.jpg?quality=75&amp;width=640&amp;auto=webp 640w\" loading=\"lazy\" alt=\"(Alamy\/PA)\" class=\"sc-1mc30lb-0 ggpMaE inline-gallery-btn\"\/><\/div><figcaption class=\"sc-1cbdeug-1 sc-1cbdeug-3 YlsWU hgzWpY\">(Alamy\/PA)<span class=\"sc-1cbdeug-7 gjqsiM\"> <!-- -->(<!-- -->Alamy\/PA<!-- -->)<\/span><\/figcaption><\/figure>\n<\/div>\n<p>Melanocyte stem cells are at the heart of this discovery. These cells reside deep within the hair follicles and serve as a reservoir for melanocytes \u2013 the pigment-producing cells responsible for hair and skin colour.<\/p>\n<p>Under normal circumstances, our melanocyte stem cells replenish these pigment-producing cells through cyclical regeneration, a process characterised by repeated phases of activity, resting and renewal in sync with the natural cycles of hair growth and loss. This grants a steady supply of pigment and thus vibrant hair colour throughout most of our lives.<\/p>\n<div class=\"sc-awdjp1-2 cbpRGD sc-awdjp1-3 image align-center\">\n<figure class=\"sc-1cbdeug-0 cXcwgU\">\n<div data-gallery-length=\"3\" class=\"sc-awdjp1-0 gYfxfP\"><img decoding=\"async\" src=\"https:\/\/static.independent.co.uk\/2025\/08\/08\/17\/15\/iStock-2183998496.jpeg\" srcset=\"https:\/\/static.independent.co.uk\/2025\/08\/08\/17\/15\/iStock-2183998496.jpeg?quality=75&amp;width=320&amp;auto=webp 320w, https:\/\/static.independent.co.uk\/2025\/08\/08\/17\/15\/iStock-2183998496.jpeg?quality=75&amp;width=640&amp;auto=webp 640w\" loading=\"lazy\" alt=\"The study has found a surprising connection between the loss of pigment in our hair and the mechanisms that can keep cancers at bay\" class=\"sc-1mc30lb-0 ggpMaE inline-gallery-btn\"\/><\/div><figcaption class=\"sc-1cbdeug-1 sc-1cbdeug-3 YlsWU hgzWpY\">The study has found a surprising connection between the loss of pigment in our hair and the mechanisms that can keep cancers at bay<span class=\"sc-1cbdeug-7 gjqsiM\"> <!-- -->(<!-- -->Getty\/iStock<!-- -->)<\/span><\/figcaption><\/figure>\n<\/div>\n<p>But every day, our cells endure assaults on its own DNA (the genetic material inside our cells) from sources such as ultraviolet radiation, chemical exposure and even our own cellular metabolism process. This cellular damage contributes to both ageing and to the risk of cancers \u2013 such as melanoma, a type of skin cancer.<\/p>\n<p>This new study sheds light on what happens when melanocyte stem cells deep within the supportive niche of the hair follicle sustain DNA damage \u2013 particularly a type of damage called double-strand breaks.<\/p>\n<p>When this happens, the melanocyte stem cells can undergo a process called \u201cseno-differentiation\u201d. In essence, this means that the stem cells irreversibly mature into pigment cells \u2013 then disappear from the stem cell pool, leading to the gradual appearance of grey in our hair.<\/p>\n<p>This protective process is tightly regulated by internal signalling pathways which allow the cells to communicate with each other. By removing these mature cells from the stem cell population, this prevents the accumulation and possible future spread of genetic mutations or DNA changes that could promote cancer.<\/p>\n<figure class=\"sc-6wesat-0 coyFhR\">\n<article class=\"sc-16sju4d-0 nAYYn sc-uqokbu-1 fqSzUj\">\n<div class=\"sc-16sju4d-4 dWJLHK\">\n<div class=\"sc-16sju4d-5 gAOUIi slot-secondary\">\n<div class=\"sc-uqokbu-6 dFInWM\">\n<div class=\"sc-uqokbu-0\">\n<p>Justin Stebbing is a Professor of Biomedical Sciences at Anglia Ruskin University.<\/p>\n<p>This article was first published by <a target=\"_blank\" href=\"https:\/\/theconversation.com\/uk\" target=\"_blank\" rel=\"noreferrer\">The Conversation<\/a> and is republished under a Creative Commons licence. Read the <a target=\"_blank\" href=\"https:\/\/theconversation.com\/how-grey-hair-and-cancer-may-be-linked-268405\" target=\"_blank\" rel=\"noreferrer\">original article.<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/figure>\n<p>In a sense, each grey hair is a small victory of bodily self-sacrifice: a cell choosing to bow out rather than risk turning malignant.<\/p>\n<p><h2>Cancer link<\/h2>\n<\/p>\n<p>The story doesn\u2019t end there, however. Not all DNA damage triggers this protective process. In their experiments, the researchers exposed melanocyte stem cells in mice to potent cancer-causing chemicals as well as UV radiation. Remarkably, under these stressors, melanocyte stem cells were found to bypass seno-differentiation altogether.<\/p>\n<p>Instead, signals from the surrounding tissues actually encouraged the damaged cells to self-renew and continue dividing \u2013 despite carrying genetic damage. This created a cellular environment ripe for the emergence of melanoma.<\/p>\n<p>This research suggests that the fate of melanocyte stem cells appears to hinge on both the specific kind of damage they receive and on the molecular cues present in their micro-environment. Stressors such as chemicals or UV light, which cause the cells\u2019 DNA strands to break, also cause the melanocyte stem cells to self-destruct by default. This same process causes grey hair.<\/p>\n<p>But when under the influence of cancer cells, these damaged melanocyte stem cells persist \u2013 creating seeds from which melanoma can grow. Scientists describe this dynamic as \u201cantagonistic fates\u201d \u2013 where the same stem cell population can take two dramatically different paths depending on the circumstances.<\/p>\n<p>Importantly, these findings reframe grey hair and melanoma not as unrelated outcomes, but as twin fates of the body\u2019s ancient struggle to balance tissue renewal and avoid cancer. Greying is not itself a shield against cancer, but instead a byproduct of a protective process that eliminates risky cells.<\/p>\n<p>Conversely, when the control mechanisms falter or are subverted by carcinogens, the door is left open for malignancy. This new understanding may also help begin to explain why we\u2019re more likely to develop cancer as we get older.<\/p>\n<div class=\"sc-awdjp1-2 cbpRGD sc-awdjp1-3 image align-center\">\n<figure class=\"sc-1cbdeug-0 cXcwgU\">\n<div data-gallery-length=\"3\" class=\"sc-awdjp1-0 fJAAkT\"><img decoding=\"async\" src=\"https:\/\/static.independent.co.uk\/2024\/11\/14\/12\/14103415-f24731f5-bf7c-4707-ad2f-6919b1fa7f79.jpg\" srcset=\"https:\/\/static.independent.co.uk\/2024\/11\/14\/12\/14103415-f24731f5-bf7c-4707-ad2f-6919b1fa7f79.jpg?quality=75&amp;width=320&amp;auto=webp 320w, https:\/\/static.independent.co.uk\/2024\/11\/14\/12\/14103415-f24731f5-bf7c-4707-ad2f-6919b1fa7f79.jpg?quality=75&amp;width=640&amp;auto=webp 640w\" loading=\"lazy\" alt=\"The findings have reframed grey hair and melanoma as part of the body\u2019s struggle against tissue renewal and avoiding cancer\" class=\"sc-1mc30lb-0 ggpMaE inline-gallery-btn\"\/><\/div><figcaption class=\"sc-1cbdeug-1 sc-1cbdeug-3 YlsWU hgzWpY\">The findings have reframed grey hair and melanoma as part of the body\u2019s struggle against tissue renewal and avoiding cancer<span class=\"sc-1cbdeug-7 gjqsiM\"> <!-- -->(<!-- -->Alamy\/PA<!-- -->)<\/span><\/figcaption><\/figure>\n<\/div>\n<p>Of course, it\u2019s crucial to note the limits of these findings. Much of the pivotal evidence comes from experiments in mice. This means research still needs to be conducted in humans to understand if our melanocyte stem cells also function in a similar way. Biological differences between species, as well as complexities of human lifestyles and genetics, mean the picture for our own hair and cancer risk is nuanced.<\/p>\n<p>Still, these discoveries open exciting avenues for both cancer research and ageing science. Understanding the signals that nudge stem cells toward differentiation or risky expansion could someday enable therapies to reinforce the body\u2019s natural safeguards, potentially lowering cancer risk as we age.<\/p>\n<p>There are broader implications as well. This information could help explain why some people develop melanoma even without having been exposed to clear risk factors \u2013 and why cancers and tissue degeneration so often go hand-in-hand in later life.<\/p>\n<p>The story of grey hair is not just about vanity or the inevitable march of time. It\u2019s about evolution, adaptation and the ceaseless vigilance of our bodies\u2019 internal guardians. Those silver strands may be telling us something profound: that amid the competition between ageing and cancer, sometimes it\u2019s worth sacrificing a pigment cell for the sake of the whole organism.<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.independent.co.uk\/life-style\/health-and-families\/grey-hair-cancer-melanoma-stem-cells-b3060448.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Want to bookmark your favourite articles and stories to read or reference later? Start your Independent Membership today. Join today Already a member? Log in Get the Well Enough newsletter with Harry Bullmore for tips on living a healthier, happier and longer life Get the Well Enough email with Harry Bullmore Get the Well Enough [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15038,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/static.independent.co.uk\/2026\/06\/26\/12\/58\/iStock-2183609330.jpeg?trim=0,0,0,0&width=1200&height=800&crop=1200:800","fifu_image_alt":"","jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_social_meta":[],"jnews_override_counter":[],"footnotes":""},"categories":[31],"tags":[2501,890,12424,1062,2864,8650,1686],"class_list":["post-15037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle","tag-cancer","tag-find","tag-grey","tag-hair","tag-link","tag-scientists","tag-surprise"],"_links":{"self":[{"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/posts\/15037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/comments?post=15037"}],"version-history":[{"count":0,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/posts\/15037\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/media\/15038"}],"wp:attachment":[{"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/media?parent=15037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/categories?post=15037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thehotedit.com\/index.php\/wp-json\/wp\/v2\/tags?post=15037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}